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Systemic Pharmacology (Second Edition)
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CNS Pharmacology
CNS Pharmacology
Master Guide
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Introduction to Anticonvulsant Drugs
Seizures defined and classified, the antiseizure drugs by chemistry, and how they act on sodium, calcium, GABA and glutamate.
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Antiseizure Barbiturates, Hydantoins & Iminostilbenes
Phenytoin and fosphenytoin, phenobarbitone and primidone, and carbamazepine, oxcarbazepine and eslicarbazepine.
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Succinimides & Lamotrigine
Ethosuximide and T-type calcium channels in absence seizures, and lamotrigine: sodium channels, rash and the valproate interaction.
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Valproic Acid, Oxazolidinediones & Benzodiazepines
The antiseizure benzodiazepines, valproic acid, and trimethadione and its congeners.
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Gabapentin, Vigabatrin & Other Antiepileptics
Epilepsy recapped, then ethosuximide, vigabatrin, tiagabine, gabapentin, pregabalin, the benzodiazepines and broad-spectrum agents.
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Antidepressants & Lithium
SSRIs, tricyclics, SNRIs, 5-HT₂ antagonists, the newer agents and MAO inhibitors, serotonin syndrome and lithium.
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Sedative–Hypnotic Drugs
Anxiolytics and hypnotics: benzodiazepines, barbiturates, the Z-drugs, melatonin agonists, buspirone, orexin antagonists and GABA-A.
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Major Tranquilizers (Antipsychotic Drugs)
Psychosis and its hypotheses, first- against second-generation drugs, mechanism, adverse effects from EPS to NMS, uses and monitoring.
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Drug Addiction & Abuse · Cannabinoids · Inhalants
Drugs of abuse classified, reward and the molecular basis of addiction, tolerance and relapse, LSD, cannabis and inhalants.
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Addiction to Opioids, Cocaine, Amphetamines, CNS Depressants & Psychedelics
How dependence works, then opioids, cocaine, the amphetamines and MDMA, alcohol and other depressants, and the psychedelics.
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Parkinsonism & Other Movement Disorders
Levodopa with carbidopa, dopamine agonists, MAO-B and COMT inhibitors, amantadine and antimuscarinics, Huntington's, tics and restless legs.